Neuropathic Pain

Nerve pain is caused by lesions or deformities of the nerve. Symptoms may include burning, tingling, numbness, and shocks of electricity. These symptoms can drastically affect a persons quality of life. Studies have shown that people with nerve pain have the highest rates of sleep problems, anxiety, and depression.

Treating nerve pain can sometimes be difficult. Oral medications, although effective, have many undesirable side effects. Topical creams for nerve pain can drastically reduce those negative effects by providing relief to the nerves located at the site of the pain while keeping systemic absorption to a minimum. Delivering the right medication to the right trigger point can decrease the amount of medication the patient uses.

Critical Care Pharmacy can combine the right medications into a topically applied cream that will treat the specific triggers that cause neuropathic pain. Our neuro-pain cream can be customized to meet an individual patients needs while drastically improving compliance and efficac y. Contact your Critical Care Pharmacy representative or pharmacist for more information about treating neuropathic pain.

Common Types of Neuropathic Pain

• Fibromyalgia
• Sciatica
• Diabetic neuropathy
• Chemo-Induced Neuropathy
• Shingles
• HIV induced neuropathy
• Neuropathy from injury

 
Ketamine acts as an NMDA antagonist and is used as an anesthetic(2), while Gabapentin, a glutamate antagonist, has been used for neuropathy widespread. Together they mitigate glutaminergic calcium influx more effectively than either agent alone.(4)

Clonidine – provides analgesic affects but is limited orally by its effects on blood pressure. Topically it also potentiates the effects of other anesthetics in the formula(3).

Amitriptyline – interferes with the way the nerve impulses are transmitted, reducing pain sensation(1).

Mefenamic Acid – an NSAID found help to reduce nerve pain while

Bupivacaine – used as a local anesthetic.

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